Madhulika Varma, M.D.

Professor of Surgery
Division of General Surgery
Chief, Section of Colorectal Surgery 
Maurice Galante, MD Distinguished Professor in Surgical Oncology
Director, UCSF Center for Pelvic Physiology 

Contact Information

(415) 885-3606 Patients & Clinic
madhulika.varma@ucsf.edu
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  • 1983-87 Brown University, Providence, RI - A.B., Human Biology
  • 1987-91 Brown University, Providence, RI - M.D.
  • 1991-97 University of California, San Francisco - Resident, Surgery
  • 1997-98 University of California, San Francisco - Chief Resident, Surgery
  • 1994-96 University of California, San Francisco - Research Fellowship, Department of Stomatology, PI
  • 1999-00 University of Minnesota, Minneapolis, MN - Fellow, Colon and Rectal Surgery
  • 2000-01 University of California, San Francisco - Fellow, Advanced Training in Clinical Research: Biostatistics & Epidemiology
  • American Board of Surgery, 1999; Recertification, 2007
  • American Board of Colon and Rectal Surgery, 2001
  • Director, UCSF Center for Pelvic Physiology
  • Program Director, UCSF Center for Colorectal Surgery
  • Anal Cancer
  • Colitis
  • Colon Cancer
  • Constipation
  • Crohn's Disease
  • Diverticulitis
  • Fecal Incontinence
  • Hemorrhoids
  • Inflammatory Bowel Disease
  • Pelvic Floor Disorders
  • Presacral Tumors
  • Rectal Cancer
  • Ulcerative Colitis

Dr. Madhulika Varma is Professor and Chief of the Section of Colorectal Surgery, Division of General Surgery at UCSF. She specializes in laparoscopic colorectal surgery, using minimally invasive techniques to treat diseases of the colon, rectum and anus. Her areas of expertise also include inflammatory bowel diseases such as ulcerative colitis, Crohn's disease and pelvic floor disorders.

 Dr. Varma is also the Director of the UCSF Center for Pelvic Physiology, which evaluates patients with fecal incontinence, constipation, pelvic floor prolapse, rectal cancer and anal fistulas. She is a member of the clinical team of the UCSF Women's Continence Center and the UCSF Center for Colitis and Crohn's Disease.

Dr. Varma earned her medical degree at Brown University School of Medicine in Providence, R.I. She completed her residency in general surgery at UCSF and spent a year at the University of Minnesota to obtain specialized training in colon and rectal surgery. She returned to the faculty at UCSF in 2000, where she completed a fellowship in Clinical Outcomes Research and Epidemiology. Her research interests include the assessment of clinical outcomes and quality of life for patients with colorectal cancer, inflammatory bowel diseases, and defecation disorders. Highly respected by her peers, Dr. Varma was named to the list of U.S. News "America's Top Doctors," a distinction reserved for the top 1% of physicians in the nation for a given specialty.

  • A Randomized, Subject and Evaluator Blinded, Sham Controlled, Multicenter Study to Evaluate Efficacy and Safety of NASHA/Dx for the Treatment of Fecal Incontinence
  • The Comprehensive Validation of the CSI (Constipation Severity Instrument) and CRQOL (Constipation-Related Quality of Life) and the Comprehensive Validation of the RCM (Rome III Constipation Module)
  • A Phase II Trial of Neoadjuvant Chemoradiation and Local Excision for uT2uN0 Rectal Cancer
  • Timing of Rectal Cancer Response to Chemoradiation
  • The Effect of Rectal Resection on Bowel, Bladder, and Sexual Functioning in Patients with Inflammatory Bowel Disease
  • A Randomized Control Trial to Examine the Efficacy of Anorectal Biofeedback
  • Prevalence of Sexual Dysfunction in Ulcerative Colitis Patients
  • Outcomes of Patients Presenting to the UCSF Center for Pelvic Physiology with Pelvic Floor Disorders
Most recent publications from a total of 53
  1. Marco MR, Zhou L, Patil S, Marcet JE, Varma MG, Oommen S, Cataldo PA, Hunt SR, Kumar A, Herzig DO, Fichera A, Polite BN, Hyman NH, Ternent CA, Stamos MJ, Pigazzi A, Dietz D, Yakunina Y, Pelossof R, Garcia-Aguilar J. Consolidation mFOLFOX6 Chemotherapy After Chemoradiotherapy Improves Survival in Patients With Locally Advanced Rectal Cancer: Final Results of a Multicenter Phase II Trial. Dis Colon Rectum. 2018 Oct; 61(10):1146-1155. View in PubMed
  2. Bailey JJ, Jordan EJ, Burke C, Ohliger MA, Wang ZJ, Van Loon K, Varma MG, Hope TA. Does Extended PET Acquisition in PET/MRI Rectal Cancer Staging Improve Results? AJR Am J Roentgenol. 2018 10; 211(4):896-900. View in PubMed
  3. Savoie MB, Paciorek A, Zhang L, Van Blarigan EL, Sommovilla N, Abrams D, Atreya CE, Bergsland EK, Chern H, Kelley RK, Ko A, Laffan A, Sarin A, Varma MG, Venook AP, Van Loon K. Vitamin D Levels in Patients with Colorectal Cancer Before and After Treatment Initiation. J Gastrointest Cancer. 2018 Jul 30. View in PubMed
  4. Bordeianou LG, Carmichael JC, Paquette IM, Wexner S, Hull TL, Bernstein M, Keller DS, Zutshi M, Varma MG, Gurland BH, Steele SR. Consensus Statement of Definitions for Anorectal Physiology Testing and Pelvic Floor Terminology (Revised). Dis Colon Rectum. 2018 Apr; 61(4):421-427. View in PubMed
  5. Varma MG. Expert Commentary on Rectal Prolapse. Dis Colon Rectum. 2017 11; 60(11):1135-1136. View in PubMed
  6. Zukotynski K, Jadvar H, Hope T, Subramaniam RM, Van Loon K, Varma M, Niederkohr RD. SNMMI Comment on the 2016 Society of Surgical Oncology "Choosing Wisely" Recommendation on the Use of PET/CT in Colorectal Cancer. J Nucl Med. 2017 Jan; 58(1):11-12. View in PubMed
  7. Matthews CA, Varma MG, Takase-Sanchez MM, Hale DS, Van Drie D, Muir T, Wells E, Jannelli M, Richter HE. Characteristics Associated With Successful Fitting of a Vaginal Bowel Control System for Fecal Incontinence. Female Pelvic Med Reconstr Surg. 2016 Sep-Oct; 22(5):359-63. View in PubMed
  8. Sarin A, Litonius ES, Naidu R, Yost CS, Varma MG, Chen LL. Successful implementation of an Enhanced Recovery After Surgery program shortens length of stay and improves postoperative pain, and bowel and bladder function after colorectal surgery. BMC Anesthesiol. 2016 08 03; 16(1):55. View in PubMed
  9. Cohan JN, Ozanne EM, Sewell JL, Hofer RK, Mahadevan U, Varma MG, Finlayson E. A Novel Decision Aid for Surgical Patients with Ulcerative Colitis: Results of a Pilot Study. Dis Colon Rectum. 2016 Jun; 59(6):520-8. View in PubMed
  10. Paquette IM, Varma M, Ternent C, Melton-Meaux G, Rafferty JF, Feingold D, Steele SR. The American Society of Colon and Rectal Surgeons' Clinical Practice Guideline for the Evaluation and Management of Constipation. Dis Colon Rectum. 2016 Jun; 59(6):479-92. View in PubMed
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