Shuvo Roy, Ph.D.

Shuvo Roy, Ph.D.
Professor, Departments of Bioengineering & Therapeutic Sciences and Surgery
UCSF Schools of Pharmacy and Medicine
Engineering Lead, Surgical Innovations Program
Director, Biodesign Laboratory
UCSF Faculty Director, UC Berkeley-UCSF Master of Translational Medicine (MTM) Program
Technical Director, The Kidney Project
 

Contact Information

1700 4th Street
San Francisco CA 94158
Phone 415-514-9666
Shuvo.Roy@ucsf.edu
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  • PhD, Electrical Engineering and Applied Physics, Case Western Reserve University, 2001
  • MS, Electrical Engineering and Applied Physics, Case Western Reserve University, 1995
  • BS, Physics, Mathematics, and Computer Science, Mount Union College, Alliance, Ohio, 1992
  • UCSF - UC Berkeley Joint Graduate Group in Bioengineering
  • Pharmaceutical Sciences and Pharmacogenomics Graduate Program (PSPG)
  • UC Berkeley - UCSF Master of Translational Medicine (MTM) Program California Institute for Quantitative Biosciences (QB3)
  • Artificial Kidney
  • Artificial Organs
  • Biocompatibility
  • Bioengineering
  • BioMEMS
  • Medical Devices
  • Microelectromechanical Systems
  • Microtextured Substrates
  • Nanotechnology
  • Renal Replacement
  • Sensors
  • Therapeutics
  • Tissue Engineering
  • Transducers

Shuvo Roy, PhD, is a bioengineer focusing on the development of medical devices to address unmet clinical needs through strong collaboration and a multidisciplinary approach.

Dr. Roy is a professor at the University of California, San Francisco in the Department of Bioengineering and Therapeutic Sciences (BTS), a joint department of the UCSF Schools of Pharmacy and Medicine, and is a faculty affiliate of the California Institute for Quantitative Biosciences (QB3). He is the director of the Biodesign Laboratory located on the Mission Bay campus. In addition, he serves as the Technical Director of The Kidney Project and is a founding member of the UCSF Pediatric Device Consortium. He has developed and currently teaches a course on medical devices, diagnostics, and therapeutics and regularly lectures on the medical device design process to UCSF graduate students and to national and international academic and industry audiences. He is the author of more than 100 publications and co-author of three book chapters, and holds multiple patents for device developments.

Before joining UCSF in 2008, Roy co-directed the BioMEMS Laboratory in the Department of Biomedical Engineering at Cleveland Clinic in Cleveland, Ohio, focusing on clinical applications of MEMS. In 1992 he earned a BS degree, magna cum laude, for triple majors in physics, mathematics, and computer science, from Mount Union College in Alliance, Ohio. In 1995, he earned an MS in electrical engineering and applied physics and, in 2001, he earned a PhD in electrical engineering and computer science, both from Case Western Reserve University in Cleveland, Ohio.

He is the recipient of a Top 40 under 40 award by Crain's Cleveland Business in 1999 and the Clinical Translation Award at the 2nd Annual BioMEMS and Biomedical Nanotechnology World 2001 meeting. In 2003, Dr. Roy was selected as a recipient of the TR100, which features the world's 100 Top Young Innovators as selected by Technology Review, the Massachusetts Institute of Technology's Magazine of Innovation. In 2004, he was presented with a NASA Group Achievement Award for his work on harsh environment MEMS. 

In 2005, Dr. Roy was named as a Who's Who in Biotechnology by Crain's Cleveland Business. In 2005 and 2007, he was recognized as a Cleveland Clinic Innovator. In 2009, he was nominated for the Biotechnology Industry Organization's Biotech Humanitarian Award, which is given in recognition of an individual who has used biotechnology to unlock its potential to improve the earth. 

In 2012, he was presented the Rising Star Award by BayBio Pantheon, and in that same year, he received the Innovation Pathway 2.0 Award from the Food and Drug Administration (FDA). Most recently, he was recognized as a Fellow by the Applied Innovation Institute in 2013.

Related Links

An Implantable Artificial Kidney: Interview with UCSF's Dr. Shuvo Roy

Improving Health By Our Own Devices (November 26, 2012)

Artificial Kidney Project at UCSF Receives $3 Million in New Funding (October 1, 2012)

New Technology to Improve Patient Care Highlighted at Dreamforce 2012 (September 24, 2012)

Health Care Game Changers to Address Dreamforce Conference (September 5, 2012)

Web-Enabled Bathroom Scale Could Monitor Heart Failure from Home (August 7, 2012)

UCSF Artificial Kidney Project Tapped for Accelerated FDA Program (April 9, 2012)

UCSF Consortium Collaborates to Invent Medical Devices for Children (November 1, 2011)

QB3 Signs Agreement to Accelerate Innovation (October 26, 2011)

  • Fellow, Applied Innovation Institute, 2013
  • Requested Nominator, Heinz Awards, 2013
  • Rising Star Award, BayBio Pantheon, 2012
  • Innovation Pathway 2.0 Award, Food and Drug Administration (FDA), 2012
  • UCSF Outstanding Faculty Mentorship Award, Finalist, University of California, San Francisco, 2012
  • mHealth Alliance Award, Vodafone Americas Foundation, 2011
  • Images of the Year Selection, Biomaterials Journal, 2009
  • Biotech Humanitarian Award Finalist, Biotechnology Industry Organization, 2009
  • Thomas G. Orr Memorial Lectureship, Southwestern Surgical Congress, 2008
  • Cleveland Clinic Innovator Award, Cleveland Clinic, 2007
  • Mentor Recognition Award, Cleveland Clinic Science Internship Program, 2006
  • Cleveland Clinic Innovator Award, Cleveland Clinic, 2005
  • Who's Who in Biotechnology, Crain's Cleveland Business, 2005
  • Ribbon Award, Outstanding Symposium Paper, MRS Fall Meeting, Materials Research Society, 2004
  • NASA Group Achievement Award, Harsh Environment MEMS, NASA, 2004
  • MIT TR100 Award, Top 100 Young Innovators, Technology Review Magazine, 2003
  • Clinical Translation Award, BioMEMS and Biomedical Nanotechnology World Meeting, 2001
  • Top 40 Under 40, Crain's Cleveland Business, 1999
  • Ruth Barber Moon Graduate Student Award, Case Western Reserve University, 1998
  • Senior Physics Prize, Mount Union College, 1992
  • William and Burdella Carl Mathematics Award, Mount Union College, 1989
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Chronic kidney failure threatens about half a million people in the U.S. alone. Donated kidneys can restore health, but they are in are in short supply.  As a result, some 350,000 people with failing kidneys are tethered to dialysis machines several days a week – a tiring, uncomfortable and expensive treatment, and one that falls far short of performing a normal kidney's functions. Shuvo Roy, a professor in the UCSF Department of Bioengineering and Therapeutic Sciences, and his colleagues are developing an implantable, fully functional artificial kidney.  

Research projects include:

  • Development of an artificial kidney
  • Development of an intravascular bioreactor for islet therapy in Type 1 diabetes patients
  • Investigation into covalent attachment of self-assembled monolayer films to enhance biocompatibility of implanted devices
  • Resorbable electronics for tissue monitoring and stimulation, and dataloggers for patient monitoring
  • Development of compact hemofilters for renal replacement therapy
  • Wireless sensing systems for load measurement
  • Focused ultrasound transducers for minimally invasive imaging and therapy
  • Building an Implantable Artificial Kidney, NIH/NIBIB - U01EB021214Sep 30, 2015 - Jun 30, 2019, Role: Principal Investigator
2014 - 2016 Roy Lab
Most recent publications from a total of 88
  1. Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges. Cell Stem Cell. 2018 Jun 01; 22(6):810-823. View in PubMed
  2. Buck AKW, Groszek JJ, Colvin DC, Keller SB, Kensinger C, Forbes R, Karp S, Williams P, Roy S, Fissell WH. Combined In Silico and In Vitro Approach Predicts Low Wall Shear Stress Regions in a Hemofilter that Correlate with Thrombus Formation In Vivo. ASAIO J. 2018 Mar/Apr; 64(2):211-217. View in PubMed
  3. Buck AKW, Goebel SG, Goodin MS, Wright NJ, Groszek JJ, Moyer J, Singh S, Bluestein D, Fissell WH, Roy S. Original article submission: Platelet stress accumulation analysis to predict thrombogenicity of an artificial kidney. J Biomech. 2018 Mar 01; 69:26-33. View in PubMed
  4. Inan OT, Baran Pouyan M, Javaid AQ, Dowling S, Etemadi M, Dorier A, Heller JA, Bicen AO, Roy S, De Marco T, Klein L. Novel Wearable Seismocardiography and Machine Learning Algorithms Can Assess Clinical Status of Heart Failure Patients. Circ Heart Fail. 2018 Jan; 11(1):e004313. View in PubMed
  5. Feinberg BJ, Hsiao JC, Park J, Zydney AL, Fissell WH, Roy S. Slit pores preferred over cylindrical pores for high selectivity in biomolecular filtration. J Colloid Interface Sci. 2018 May 01; 517:176-181. View in PubMed
  6. Ferrell N, Cheng J, Miao S, Roy S, Fissell WH. Orbital Shear Stress Regulates Differentiation and Barrier Function of Primary Renal Tubular Epithelial Cells. ASAIO J. 2017 Dec 11. View in PubMed
  7. Iqbal Z, Moses W, Kim S, Kim EJ, Fissell WH, Roy S. Sterilization effects on ultrathin film polymer coatings for silicon-based implantable medical devices. J Biomed Mater Res B Appl Biomater. 2017 Nov 06. View in PubMed
  8. Dharia A, Abada E, Feinberg B, Yeager T, Moses W, Park J, Blaha C, Wright N, Padilla B, Roy S. Silicon Micropore-Based Parallel Plate Membrane Oxygenator. Artif Organs. 2018 Feb; 42(2):166-173. View in PubMed
  9. Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S. Correction: An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport. Lab Chip. 2017 06 27; 17(13):2334. View in PubMed
  10. Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S. An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport. Lab Chip. 2017 05 16; 17(10):1778-1792. View in PubMed
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